Controlling the Spiking Activity of Autaptic Hodgkin-Huxley Neuron by Potassium Ion Channel Blocking

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Abstract


We investigated the spiking activity of autaptic Hodgkin-Huxley neuron with a tunable fraction of blocked potassium ion channels. We consider an electrical autapse expressed by its coupling strength and delay time. We showed that there exists a double coherence resonance induced by autaptic time delay at an intermediate autaptic conductance level, as well potassium ion channel blocking impairs this behavior at a certain extent at a specific range of autaptic time delay. In the light of the obtained results; we concluded that the reduction of the number of active potassium ion channels destroys the spiking regularity of a single neuron in the presence of electrical autapse. 


Keywords


Autapse; Potassium ion channel blocking; Spiking activity; Hodgkin-Huxley neuron.

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DOI: http://dx.doi.org/10.7212%2Fzkufbd.v7i2.1099

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