Controlling the Spiking Activity of Autaptic Hodgkin-Huxley Neuron by Potassium Ion Channel Blocking
We investigated the spiking activity of autaptic Hodgkin-Huxley neuron with a tunable fraction of blocked potassium ion channels. We consider an electrical autapse expressed by its coupling strength and delay time. We showed that there exists a double coherence resonance induced by autaptic time delay at an intermediate autaptic conductance level, as well potassium ion channel blocking impairs this behavior at a certain extent at a specific range of autaptic time delay. In the light of the obtained results; we concluded that the reduction of the number of active potassium ion channels destroys the spiking regularity of a single neuron in the presence of electrical autapse.
© 2011 Karaelmas Fen ve Mühendislik Dergisi